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Welcome to the Großhans Lab at Friedrich Miescher Institute for Biomedical Research (FMI), Basel, Switzerland 🇨🇭

Proper development of tissues, organs, and entire organisms is a complex process that relies on precise timing and coordination of cell fate choices. Developmental clocks provide temporal and spatial structures to generate these events and ensure their synchrony. How such clocks function is only beginning to emerge. What are their properties? What are the components that make them run, and how are they wired? We use C. elegans and mammalian cells to address these questions, using various approaches from molecular biology and microscopy to mathematical modeling and bioinformatics.